中文名 | 人参皂苷 Rf |
英文名 | Ginsenoside Rf |
别名 | 人参皂荚RF 人参皂甙 RF 人参皂苷 Rf 人参皂苷-RF 人参皂苷RF(标准品) 人参皂苷 RF, 来源于人参 GINSENOSIDE RF 人参皂苷RF |
英文别名 | PANAXOSIDE RF Panaxoside RF Ginsenoside Rf GINSENOSIDE RF Ginsenoside RF GINSENOSIDE Rf hplc GINSENOSIDE RF WITH HPLC β-D-Glucopyranoside, (3β,6α,12β)-3,12,20-trihy droxydammar-24-en-6-yl 2-O-β-D-glucopyranosyl- (20S)-6α-(2-O-β-D-Glucopyranosyl-β-D-glucopyranosyloxy)-5α-dammara-24-ene-3β,12β,20-triol (3β,6α,12β)-3,12,20-Trihydroxydammar-24-en-6-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside (3beta,6alpha,12beta)-3,12,20-trihydroxydammar-24-en-6-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside (6beta,8xi,9xi,12alpha,13alpha,14beta,17beta)-3,12-dihydroxy-17-[(1S,4E)-1-hydroxy-1,5-dimethylhept-4-en-1-yl]-4,4,10,14-tetramethylgonan-6-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside |
CAS | 52286-58-5 |
化学式 | C42H72O14 |
分子量 | 801.02 |
InChI | InChI=1/C42H72O14/c1-8-20(2)10-9-13-42(7,52)21-11-14-40(5)23-17-25(36-39(3,4)28(46)12-15-41(36,6)22(23)16-24(45)29(21)40)53-38-35(33(50)31(48)27(19-44)55-38)56-37-34(51)32(49)30(47)26(18-43)54-37/h10,21-38,43-52H,8-9,11-19H2,1-7H3/b20-10+/t21-,22?,23?,24-,25+,26+,27+,28?,29+,30+,31+,32-,33-,34+,35+,36?,37-,38+,40+,41+,42-/m0/s1 |
密度 | 1.33±0.1 g/cm3(Predicted) |
熔点 | 197~198℃ |
沸点 | 912.3±65.0 °C(Predicted) |
比旋光度 | +6.99°(c=1.00,methanol) |
闪点 | 510.8°C |
蒸汽压 | 0mmHg at 25°C |
溶解度 | 甲醇 (微溶) 、吡啶 (微溶) |
折射率 | 1.601 |
酸度系数 | 12.85±0.70(Predicted) |
存储条件 | Sealed in dry,2-8°C |
外观 | 整洁 |
颜色 | White to Off-White |
物化性质 | 来源于五加科植物人参Panax ginseng C. A. Mey.的干燥根 |
MDL号 | MFCD00210509 |
危险品标志 | Xn - 有害物品 |
风险术语 | 22 - 吞食有害。 |
安全术语 | S2 - 避免儿童触及。 S45 - 若发生事故或感不适,立即就医(可能的话,出示其标签)。 S24/25 - 避免与皮肤和眼睛接触。 |
WGK Germany | 3 |
RTECS | LY9536900 |
海关编号 | 29389090 |
参考资料 展开查看 | 1. 苗瑞, 吴冬雪, 王秋颖,等. 基于多壁碳纳米管的人参皂苷快速分离[J]. 高等学校化学学报, 2018. 2. 余健, 徐晓珍, 顾利强,等. 高效液相色谱-串联质谱法同时测定参麦注射液中9种皂苷[J]. 中华中医药学刊, 2014. 3. 张琰, 李方彤, 韩铭鑫,等. 通过RRLC-Q-TOF MS和UPLC-QQQ MS分析原人参三醇型皂苷在人肠道菌群中的代谢产物[J]. 质谱学报, 2020(1):66-75. 4. 张博, 孙秀丽, 郭云龙,等. 液质联用技术分析不同产地不同年限人参的化学成分[J]. 中国实验方剂学杂志, 2020年26卷8期, 206-212页, ISTIC PKU CSCD CA, 2020. 5. 杨林, 徐晓珍, 陈劲柏,等. UHPLC法同时测定参麦注射液中8种人参皂苷[J]. 中成药, 2019. 6. 温宝庆,李文庆,周妙霞,林坤霞,汪小东,钱正明.茯神饮中化学成分的核壳色谱-四级杆飞行时间质谱联用鉴定和分析[J].时珍国医国药,2020,31(06):1334-1338. 7. 纪万里,周泽华,王婷婷,安叡,梁琨,王新宏.基于UPLC-LTQ-Orbitrap-MS方法分析半夏泻心汤化学成分[J].药物分析杂志,2020,40(10):1736-1750. 8. Zhengming Qian, Qi Huang, Chunhong Li, Jing Chen, Gang Li, Hongyan Ma & Juying Xie (2020) Analysis of ginseng root and leaf by multiple columns and detections liquid chromatography, Journal of Liquid Chromatography & Related Technologies, 43:13-14, 464-473 9. Chen, Jiali, et al. "Ginsenosides and amino acids in flavored ginseng chips as affected by food formulation and processing technology." LWT-Food Science and Technology 62.1 (2015): 517-524.https://doi.org/10.1016/j.lwt.2014.10.047 10. [IF=6.06] Jiahong Han et al."Compatibility effects of ginseng and Ligustrum lucidum Ait herb pair on hematopoietic recovery in mice with cyclophosphamide-induced myelosuppression and its material basis."J Ginseng Res. 2020 Mar;44:291 11. [IF=6.06] Yang Xiu et al."Simultaneous determination and difference evaluation of 14 ginsenosides in Panax ginseng roots cultivated in different areas and ages by high-performance liquid chromatography coupled with triple quadrupole mass spectrometer in the multipl 12. [IF=5.34] Shan-Shan Zhou et al."Stronger anti-obesity effect of white ginseng over red ginseng and the potential mechanisms involving chemically structural/compositional specificity to gut microbiota."Phytomedicine. 2020 Aug;74:152761 13. [IF=4.952] Jiali Chen et al."Ginsenosides and amino acids in flavored ginseng chips as affected by food formulation and processing technology."Lwt Food Sci Technol. 2015 Jun;62:517 14. [IF=4.36] Bin Ma et al."Sulfur fumigation reducing systemic exposure of ginsenosides and weakening immunomodulatory activity of ginseng."J Ethnopharmacol. 2017 Jan;195:222 15. [IF=3.935] Shan-Shan Zhou et al."Synchronous characterization of carbohydrates and ginsenosides yields deeper insights into the processing chemistry of ginseng."J Pharmaceut Biomed. 2017 Oct;145:59 16. [IF=6.558] Qingqing Song et al."Binary code, a flexible tool for diagnostic metabolite sequencing of medicinal plants."Anal Chim Acta. 2019 Dec;1088:89 17. [IF=6.06] Zhenzhuo Li et al."Ginsenosides repair UVB-induced skin barrier damage in BALB/c hairless mice and HaCaT keratinocytes."J Ginseng Res. 2021 May;: 18. [IF=5.878] Jianbo Chen et al."Protection by ginseng saponins against cyclophosphamide-induced liver injuries in rats by induction of cytochrome P450 expression and mediation of the l-arginine/nitric oxide pathway based on metabolomics."Phytother Res. 2021 Jun;35(6): 19. [IF=5.396] Hui Wang et al."Ginsenoside extract from ginseng extends lifespan and health span in Caenorhabditis elegans."Food Funct. 2021 Aug;12(15):6793-6808 20. [IF=5.34] You-Ping Wu et al."Evidences for the mechanism of Shenmai injection antagonizing doxorubicin-induced cardiotoxicity."Phytomedicine. 2021 Jul;88:153597 21. [IF=4.411] Jianbo Chen et al."Neuroprotective Effects of Red Ginseng Saponins in Scopolamine-Treated Rats and Activity Screening Based on Pharmacokinetics."Molecules. 2019 Jan;24(11):2136 22. [IF=4.142] Wang Chenxi et al."Rapid discovery of potential ADR compounds from injection of total saponins from Panax notoginseng using data-independent acquisition untargeted metabolomics."Analytical And Bioanalytical Chemistry. 2021 Oct 26 23. [IF=3.935] Ruimei Lin et al."Global identification and determination of the major constituents in Kai-Xin-San by ultra-performance liquid chromatography-quadrupole-Orbitrap mass spectrometry and gas chromatography-mass spectrometry."J Pharmaceut Biomed. 2021 Nov;206 24. [IF=3.882] Kunpeng Yin et al."Lanthanide Metal–Organic Framework-Based Fluorescent Sensor Arrays to Discriminate and Quantify Ingredients of Natural Medicine."Langmuir. 2021;37(17):5321–5328 25. [IF=3.659] Zhang Sheng et al."Protective effect of Shenmai injection on doxorubicin-induced cardiotoxicity via regulation of inflammatory mediators."Bmc Complem Altern M. 2019 Dec;19(1):1-10 26. [IF=3.645] Mengmeng Jia et al."UHPLC coupled with mass spectrometry and chemometric analysis of Kang-Ai injection based on the chemical characterization, simultaneous quantification, and relative quantification of 47 herbal alkaloids and saponins."J Sep Sci. 2020 Ju 27. [IF=3.361] Yuhao Zhang et al."An integrated approach for structural characterization of Gui Ling Ji by traveling wave ion mobility mass spectrometry and molecular network."Rsc Adv. 2021 Apr;11(26):15546-15556 28. [IF=2.408] Fang-Tong Li et al."In Vitro Effects of Ginseng and the Seed of Zizyphus jujuba var. spinosa on Gut Microbiota of Rats with Spleen Deficiency."Chem Biodivers. 2020 Sep;17(9):e2000199 29. [IF=1.312] Zhengming Qian et al."Analysis of ginseng root and leaf by multiple columns and detections liquid chromatography."Journal Of Liquid Chromatography & Related Technologies. 2020 Mar 02 30. [IF=4.432] Shuai Zhang et al."Ginsenoside Rf inhibits human tau proteotoxicity and causes specific LncRNA, miRNA and mRNA expression changes in Caenorhabditis elegans model of tauopathy."Eur J Pharmacol. 2022 May;922:174887 31. [IF=6.06] Qingxia Huang et al."Major ginsenosides from Panax ginseng promote aerobic cellular respiration and SIRT1-mediated mitochondrial biosynthesis in cardiomyocytes and neurons."J Ginseng Res. 2022 Feb;: 32. [IF=7.514] Di Qu et al."Sediment formation and analysis of the main chemical components of aqueous extracts from different parts of ginseng roots."Food Chem. 2022 Jan;:132146 33. [IF=5.811] He Zhang et al."Prevention Effect of Protopanaxadiol-Type Saponins Saponins and Protopanaxatriol-Type Saponins on Myelosuppression Mice Induced by Cyclophosphamide.."Frontiers in Pharmacology. 2022 Apr;13:845034-845034 34. [IF=4.35] Di Qu et al."Analysis of Key Chemical Components in Aqueous Extract Sediments of Panax Ginseng at Different Ages."Foods. 2022 Jan;11(8):1161 35. [IF=6.576] Rensong Huang et al."Studies on Bioactive Components of Red Ginseng by UHPLC-MS and Its Effect on Lipid Metabolism of Type 2 Diabetes Mellitus."Frontiers in Nutrition. 2022; 9: 865070 |
微信搜索化工百科或扫描下方二维码,添加化工百科小程序,随时随地查信息!